Description

2,3-Bis(Chloromethyl)-Pyrazine is a versatile and reactive halogenated heterocyclic building block. This compound is valued for its ability to introduce the pyrazine moiety and undergo further functionalization, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyrazine core provides specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating complex chelating ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Building block for the synthesis of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,3-Bis(Chloromethyl)-Pyrazine
CAS No.	51043-75-5
Molecular Formula	C6H6Cl2N2
Molecular Weight	177.03 g/mol
Synonyms	2,3-Bis(chloromethyl)pyrazine; Pyrazine, 2,3-bis(chloromethyl)-; 2,3-Di(chloromethyl)pyrazine; 2,3-Pyrazinedimethanol, dichloride; 2,3-Bis(chloromethyl)-1,4-diazine
EINECS	Contact for details

Quality Control

Our 2,3-Bis(Chloromethyl)-Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.