Description

(3Ar,4R,6Z,10E,11Ar)-6-Acetoxymethyl-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-10-Methyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel therapeutic agents. It serves as a key building block for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a scaffold or starting material for structure-activity relationship (SAR) studies to develop new bioactive molecules.
• Process Development & Scale-Up: Serves as a reference standard and key material for optimizing synthetic routes from laboratory to pilot plant scale.
• Biochemical Research: Employed in studies investigating the mechanism of action of sesquiterpene lactones and their interaction with biological targets.
• Fine Chemical Synthesis: Utilized in the production of specialized, high-value chemical entities for advanced material science and agrochemical research.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in compliant laboratories.

Basic Information

Item	Details
Product Name	(3Ar,4R,6Z,10E,11Ar)-6-Acetoxymethyl-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-10-Methyl-3-Methylenecyclodeca[B]Furan-2(3H)-One
CAS No.	50886-56-1
Molecular Formula	C₁₇H₂₂O₅
Molecular Weight	306.36 g/mol
Synonyms	6-Acetoxymethyl-3A,4,5,8,9,11A-hexahydro-4-hydroxy-10-methyl-3-methylenecyclodeca[B]furan-2(3H)-one; (3aR,4R,6Z,10E,11aR)-6-(Acetoxymethyl)-3a,4,5,8,9,11a-hexahydro-4-hydroxy-10-methyl-3-methylidenecyclodeca[b]furan-2(3H)-one; A sesquiterpene lactone acetate derivative; Cyclodeca[b]furan-2(3H)-one derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (3Ar,4R,6Z,10E,11Ar)-6-Acetoxymethyl-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-10-Methyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.