Description

Pi(16:0/18:1) is a high-purity phosphatidylinositol (PI) lipid, a critical component of cellular membranes and a key signaling molecule. Its specific fatty acid composition (palmitic acid at the sn-1 position and oleic acid at the sn-2 position) makes it a valuable standard and reagent for research into lipid metabolism, signal transduction, and membrane biophysics. This product is essential for pharmaceutical R&D, academic biochemistry laboratories, and manufacturers of lipid-based drug delivery systems such as liposomes.

Application

• Biochemical Research Standard: Used as a reference standard in lipidomics, mass spectrometry, and chromatography for the identification and quantification of phosphatidylinositols in biological samples.
• Cell Signaling Studies: Serves as a substrate or precursor in the study of phosphoinositide signaling pathways, including those involving PI kinases and phospholipases.
• Liposome & Nanoparticle Formulation: Incorporated into lipid bilayers to create model membranes or functionalized drug delivery vehicles for targeted therapy research.
• Enzyme Activity Assays: Acts as a specific substrate for assays measuring the activity of enzymes like phospholipase C or phosphatidylinositol-specific phospholipase.
• Membrane Protein Studies: Used to create lipid environments that stabilize membrane proteins for structural and functional analysis.
• Nutritional & Cosmetic Research: Investigated for its potential bioactive properties in specialized nutraceutical and advanced cosmetic formulations.

Basic Information

Product Name	Pi(16:0/18:1)
CAS No.	50730-13-7
Molecular Formula	C47H89O13P
Molecular Weight	885.18 g/mol
Synonyms	1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-myo-inositol); POPI; Phosphatidylinositol (16:0/18:1); PI(16:0/18:1(9Z)); 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoinositol; (3-sn-Phosphatidyl)inositol (POPI); L-α-Phosphatidylinositol (palmitoyl, oleoyl)
EINECS	Contact for details

Quality Control

Every batch of Pi(16:0/18:1) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), fatty acid profile, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	16:0 (~45-55%), 18:1 (~45-55%)
Solubility	Soluble in chloroform, methanol, ethanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.