Description

1-Piperazinecarboxylic Acid, Phenyl Ester is a versatile chemical building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its piperazine core and activated phenyl ester group, making it a key precursor for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing piperazine or piperidine moieties, which are common in central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the piperazine structure imparts specific biological activity.
• Peptide Mimetics & Drug Discovery: Serves as a scaffold or linker in medicinal chemistry for creating peptide analogs and small molecule libraries for high-throughput screening.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties for coatings, adhesives, or advanced materials.
• Chemical Research & Development: Employed as a versatile reagent in academic and industrial labs for exploring new synthetic pathways and novel heterocyclic compounds.
• Ligand & Catalyst Preparation: Useful for synthesizing complex ligands for metal catalysis or functional materials used in asymmetric synthesis.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, Phenyl Ester
CAS No.	50606-33-2
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	Phenyl Piperazine-1-carboxylate; Piperazine-1-carboxylic Acid Phenyl Ester; Carbamic acid, 1-piperazinyl-, phenyl ester; 1-Carboxypiperazine Phenyl Ester; Phenyl 1-Piperazinecarboxylate; Phenyl N-Piperazinylcarbamate; 1-Piperazinecarboxylic acid phenylester; Phenyl piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, Phenyl Ester is produced and tested under strict quality management systems. We provide material that meets high-purity standards suitable for research and industrial synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures batch-to-batch consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.