Description

5-(Trifluoromethyl)Piperidin-2-One is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique combination of the piperidinone scaffold and the electron-withdrawing trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the CF₃ group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a building block for fluorinated probes and tags used in imaging and diagnostic applications.

Basic Information

Product Name	5-(Trifluoromethyl)Piperidin-2-One
CAS No.	50549-24-1
Molecular Formula	C₆H₈F₃NO
Molecular Weight	167.13 g/mol
Synonyms	5-(Trifluoromethyl)-2-piperidinone; 5-(Trifluoromethyl)piperidin-2-one; 2-Piperidinone, 5-(trifluoromethyl)-; 5-Trifluoromethyl-2-piperidone; α,α,α-Trifluoro-2-oxo-5-piperidine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Piperidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.