Description

4-Methyl-Piperazine-1-Carbonitrile is a versatile and high-value organic building block featuring a piperazine ring substituted with both a methyl group and a nitrile functionality. This unique structure makes it a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including kinase inhibitors, antipsychotics, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides due to its reactive nitrile and secondary amine groups.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other specialty organic compounds.
• Research & Development: A valuable reagent for medicinal chemistry, combinatorial chemistry, and academic research exploring new chemical entities.
• Polymer Modification: Can be used to introduce functional groups into polymer chains to alter material properties.

Basic Information

Product Name	4-Methyl-Piperazine-1-Carbonitrile
CAS No.	50451-22-4
Molecular Formula	C6H11N3
Molecular Weight	125.17 g/mol
Synonyms	1-Cyano-4-methylpiperazine; 4-Methyl-1-piperazinecarbonitrile; N-Cyano-N'-methylpiperazine; 1-Piperazinecarbonitrile, 4-methyl-; 4-Methylpiperazine-1-carbonitrile; Methylpiperazine carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Methyl-Piperazine-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.