Description

2-Bromo-3,3-Dimethylbutanoic Acid is a versatile brominated carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique steric and electronic properties imparted by the bromine atom and the tertiary butyl group, making it an essential intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sterically hindered carboxylic acid moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Peptidomimetics Research: Employed to incorporate non-natural, sterically demanding amino acid analogs into peptide chains for drug discovery.
• Polymer Modification: Acts as a functional monomer or chain-transfer agent for creating specialty polymers with specific bromine functionality.
• Organic Synthesis Building Block: Utilized in various name reactions, such as halogen-metal exchanges or coupling reactions, to create complex organic molecules.

Basic Information

Product Name	2-Bromo-3,3-Dimethylbutanoic Acid
CAS No.	50364-40-4
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	2-Bromo-3,3-dimethylbutyric acid; 3,3-Dimethyl-2-bromobutanoic acid; α-Bromo-3,3-dimethylbutyric acid; NSC 163082; Butanoic acid, 2-bromo-3,3-dimethyl-; 2-Bromo-3,3-dimethylbutanoate
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,3-Dimethylbutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure containers are kept upright and sealed to prevent moisture ingress and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.