Description

D-Hydroorotic Acid is a key intermediate in the biosynthesis of pyrimidine nucleotides, serving as a crucial building block for more complex biochemical pathways. Its high purity and consistent quality are essential for ensuring reliable results in research and manufacturing processes. This compound is primarily utilized by the pharmaceutical, biotechnology, and fine chemical synthesis industries for applications ranging from active pharmaceutical ingredient (API) development to biochemical research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of pyrimidine-based active pharmaceutical ingredients (APIs) and nucleoside analogs.
• Biochemical Research: Used as a standard or substrate in enzymatic studies and metabolic pathway investigations related to nucleotide synthesis.
• Fine Chemical Synthesis: Serves as a versatile building block for the preparation of more complex heterocyclic compounds and specialty chemicals.
• Nutritional Supplement Research: Investigated for its potential role and metabolism in relation to orotic acid and related nutritional compounds.
• Reference Standard: Employed as a high-purity analytical reference standard in quality control laboratories for HPLC, LC-MS, or NMR.

Basic Information

Product Name	D-Hydroorotic Acid
CAS No.	5988-53-4
Molecular Formula	C5H6N2O4
Molecular Weight	158.11 g/mol
Synonyms	(S)-1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid; (S)-4-Carboxy-2,6-dioxo-1,2,3,6-tetrahydropyrimidine; D-4-Carboxyuracil; D-Orotic Acid; (S)-Orotic Acid; D-1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid; L-Orotic Acid (enantiomer)
EINECS	227-818-3

Quality Control

Our D-Hydroorotic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.