Description

n-Oleoyl-D-Sphingosine CAS NO 5966-28-9 is a chemically defined, high-purity ceramide analog, specifically an N-acylated derivative of D-sphingosine. This compound is a critical building block in lipid biochemistry research and advanced cosmetic formulations, valued for its structural authenticity and biological relevance. It is primarily utilized by researchers in life sciences and product developers in the personal care industry seeking to study or replicate natural skin barrier functions.

Application

• Biochemical Research: Used as a standard or substrate in studies of sphingolipid metabolism, cell signaling pathways, and membrane biology.
• Cosmetic Science: Serves as a key active ingredient in premium skincare formulations aimed at restoring the skin's lipid barrier, improving hydration, and reducing transepidermal water loss.
• Pharmaceutical Development: Investigated as a potential component in topical drug delivery systems and therapeutic agents targeting skin disorders.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for the identification and quantification of ceramides.
• Lipidomics: An essential component in lipidomic profiling kits and studies aiming to understand lipid composition in biological samples.

Basic Information

Product Name	n-Oleoyl-D-Sphingosine
CAS No.	5966-28-9
Molecular Formula	C36H69NO3
Molecular Weight	563.94 g/mol
Synonyms	N-Oleoylsphingosine; Ceramide (d18:1/18:1(9Z)); (2S,3R,4E)-2-(9Z-Octadecenoylamino)-4-octadecene-1,3-diol; D-erythro-Sphingosine, N-(9Z-octadecenoyl)-; N-[(E,2S,3R)-1,3-Dihydroxyoctadec-4-en-2-yl]oleamide; Oleoyl sphingosine; Ceramide EOS; N-(9Z-Octadecenoyl)-D-erythro-sphingosine
EINECS	Contact for details

Quality Control

Our n-Oleoyl-D-Sphingosine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.