Description

(3Ar,4Aα,9Aα)-3A,4,4A,5,6,7,8,8A,9,9A-Decahydro-5α,8α-Dihydroxy-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is a complex, high-purity sesquiterpene lactone derivative with a unique fused ring structure. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold for synthetic organic chemistry. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel therapeutic agents, particularly in anti-inflammatory and anticancer research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its complex molecular architecture for bioactivity.
• Fine Chemical Research: Acts as a sophisticated starting material or reference standard in academic and industrial organic synthesis projects.
• Natural Product Analog Development: Provides a core structure for creating analogs of biologically active natural sesquiterpenoids.
• Material Science Precursor: Investigated for the synthesis of specialized polymers or ligands with unique chemical properties.

Basic Information

Product Name	(3Ar,4Aα,9Aα)-3A,4,4A,5,6,7,8,8A,9,9A-Decahydro-5α,8α-Dihydroxy-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One
CAS No.	5945-43-7
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	Alantolactone; Inula Helenium Lactone; Helenin; Elecampane Camphor; (3aR,4aS,9aS)-3a,4,4a,5,6,7,8,8a,9,9a-Decahydro-5,8a-dihydroxy-3,6,9-trimethylnaphtho[2,3-b]furan-2(3H)-one; 6-Hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one (related structure); Isoalantolactone (isomer)
EINECS	227-707-4

Quality Control

Every batch of our (3Ar,4Aα,9Aα)-3A,4,4A,5,6,7,8,8A,9,9A-Decahydro-5α,8α-Dihydroxy-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards for pharmaceutical and research applications. Specifications can be aligned with customer-specific requirements for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.