Description

3-[(4-Hydroxyphenyl)Methyl]Piperazine-2,5-Dione is a specialized heterocyclic organic compound featuring a piperazinedione core substituted with a 4-hydroxyphenylmethyl group. This unique structure makes it a valuable pharmacophore and synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Peptidomimetic Synthesis: Used in the design and construction of peptide analogs and mimetics due to its constrained dipeptide-like structure.
• Fine Chemical Production: An intermediate for creating advanced, high-value specialty chemicals with specific biological or material properties.
• Bioconjugation & Probe Development: Potential utility in creating labeled compounds or probes for biochemical and diagnostic applications.

Basic Information

Product Name	3-[(4-Hydroxyphenyl)Methyl]Piperazine-2,5-Dione
CAS No.	5845-66-9
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	3-(4-Hydroxybenzyl)piperazine-2,5-dione; 3-(p-Hydroxybenzyl)-2,5-piperazinedione; 3-(4-Hydroxybenzyl)-2,5-diketopiperazine; 3-(4-Hydroxybenzyl)DKP; 3-(4-Hydroxybenzyl)-2,5-dioxopiperazine; 3-(4-Hydroxybenzyl)piperazine-2,5-diketone; 4-Hydroxybenzyl-DKP; Hph-DKP
EINECS	Contact for details

Quality Control

Our 3-[(4-Hydroxyphenyl)Methyl]Piperazine-2,5-Dione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.