Description

Methyl Oxalyl Chloride CAS NO 5781-53-3 is a highly reactive acid chloride derivative of oxalic acid, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the methyl oxalyl moiety, enabling the construction of complex molecules for pharmaceuticals and agrochemicals. This reagent is essential for research chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries seeking to develop new active ingredients and intermediates.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing heterocyclic scaffolds.
• Building block for agrochemicals, including herbicides and fungicides, where it is used to create specific amide or ester functionalities.
• Reagent in peptide coupling and acylation reactions to modify molecular structures.
• Starting material for the production of dyes, pigments, and photoactive compounds.
• Used in laboratory-scale research for method development and exploring new synthetic pathways.
• Intermediate in the manufacture of specialty polymers and performance chemicals.

Basic Information

Product Name	Methyl Oxalyl Chloride
CAS No.	5781-53-3
Molecular Formula	C3H3ClO3
Molecular Weight	122.51 g/mol
Synonyms	Methyl Oxalyl Chloride; Methyl Oxaloyl Chloride; Methyl Oxalyl Chloride; Methyl Oxalochloridate; Oxalic Acid Methyl Ester Chloride; Methyl Oxalate Chloride; Chlorooxoacetic Acid Methyl Ester; Methyl Chlorooxoacetate
EINECS	227-300-9

Quality Control

Our Methyl Oxalyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use in fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.