Description

4-(2-Chlorodibenzo(Bf)(1,4)Thiazepin-11-Yl)Piperazine is a high-purity pharmaceutical intermediate and research chemical of significant synthetic importance. This compound serves as a critical building block in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacology research domains. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel dibenzothiazepine derivatives with potential antipsychotic or neuroleptic activity.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new CNS-targeting drug candidates.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical manufacturing.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding profiles and biochemical pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	4-(2-Chlorodibenzo(Bf)(1,4)Thiazepin-11-Yl)Piperazine
CAS No.	5747-63-7
Molecular Formula	C19H16ClN3S
Molecular Weight	353.87 g/mol
Synonyms	11-Piperazinyl-2-chlorodibenzo[b,f][1,4]thiazepine; 2-Chloro-11-(1-piperazinyl)dibenzo[b,f][1,4]thiazepine; 2-Chloro-11-piperazin-1-yldibenzo[b,f][1,4]thiazepine; Clothiapine Impurity; Clothiapine Related Compound A; Dibenzo[b,f][1,4]thiazepin-11-amine, 2-chloro-N-1-piperazinyl-; NSC 163049
EINECS	Contact for details

Quality Control

Our 4-(2-Chlorodibenzo(Bf)(1,4)Thiazepin-11-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.