Description

3Beta-Hydroxy-5-Androsten-17-One 3-Glucuronide is a key steroid glucuronide conjugate, specifically the 3-O-glucuronide of dehydroepiandrosterone (DHEA). This compound is of significant importance as a major metabolite in steroid hormone profiling and metabolic studies. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, clinical diagnostics, and life science sectors, enabling precise analysis and development.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the quantification of DHEA metabolites in bioanalytical assays.
• Clinical Diagnostics: Essential calibrator and control for LC-MS/MS and immunoassay kits measuring steroid hormone profiles in urine and serum.
• Endocrinology Research: Used in studies investigating androgen metabolism, sulfatase pathways, and hormonal disorders.
• Doping Control: Reference compound for anti-doping laboratories to detect the misuse of endogenous steroids like DHEA.
• Biochemical Synthesis: Serves as a high-purity intermediate for the synthesis of more complex steroid conjugates and labeled analogs.
• Forensic Toxicology: Utilized in method development and validation for the accurate identification of steroid metabolites.

Basic Information

Product Name	3Beta-Hydroxy-5-Androsten-17-One 3-Glucuronide
CAS No.	5716-14-3
Molecular Formula	C25H36O8
Molecular Weight	464.55 g/mol
Synonyms	DHEA 3-Glucuronide; Dehydroepiandrosterone 3-Glucuronide; 3β-Hydroxyandrost-5-en-17-one 3-glucuronide; Androst-5-en-3β-ol-17-one 3-β-D-glucopyranosiduronic acid; Prasterone 3-glucuronide; 5-Androsten-3β-ol-17-one 3-glucuronide; DHEA-G; DHEA-3G
EINECS	Contact for details

Quality Control

Our 3Beta-Hydroxy-5-Androsten-17-One 3-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.