Description

Piperazine-1-Ethanol Dihydrochloride is a versatile and high-purity organic salt derivative of piperazine, widely utilized as a key synthetic intermediate and building block in advanced chemical synthesis. Its primary value lies in its dual functional groups, which enable its use in constructing complex molecular architectures, particularly in pharmaceutical development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for API synthesis and novel compound discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, antihistamines, and anthelmintic agents.
• Chemical Synthesis Reagent: Used in organic synthesis for introducing the piperazine-ethanol moiety into larger molecules, facilitating the creation of novel compounds with potential biological activity.
• Agrochemical Research: Serves as a precursor in the development of new pesticides, herbicides, and plant growth regulators that require piperazine-based structures.
• Ligand and Catalyst Preparation: Employed in the preparation of chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Bioconjugation Chemistry: Utilized in the development of linkers for bioconjugation, connecting biomolecules to drugs, dyes, or solid supports.

Basic Information

Product Name	Piperazine-1-Ethanol Dihydrochloride
CAS No.	5712-71-0
Molecular Formula	C6H14N2O·2HCl
Molecular Weight	199.11 g/mol
Synonyms	1-(2-Hydroxyethyl)piperazine Dihydrochloride; 2-(Piperazin-1-yl)ethanol Dihydrochloride; N-(2-Hydroxyethyl)piperazine Dihydrochloride; Piperazineethanol Dihydrochloride; 1-Piperazineethanol Dihydrochloride; Ethanol, 2-(1-piperazinyl)-, dihydrochloride; UNII-9Q2K9N8V8F
EINECS	227-179-8

Quality Control

Our Piperazine-1-Ethanol Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency, suitable for research and commercial-scale synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.