Description

1,2-Dihexadecanoyl-Rac-Glycero-3-Phosphoethanolamine CAS NO 5681-36-7 is a high-purity synthetic phospholipid, specifically a phosphatidylethanolamine (PE) derivative with two palmitoyl (C16:0) fatty acid chains. This compound is a critical building block for creating advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, well-defined lipid components for formulation development and fundamental biophysical studies.

Application

• Liposome & Nanoparticle Formulation: A key structural phospholipid for constructing liposomal drug delivery vehicles, mRNA-LNPs (lipid nanoparticles), and other nanocarriers for targeted therapeutic delivery.
• Biomembrane Research: Used to create model membrane systems (e.g., vesicles, supported lipid bilayers) for studying membrane protein interactions, fusion processes, and cellular membrane dynamics.
• Cell Culture & Transfection Reagents: A component in complex lipid mixtures for formulating non-viral transfection reagents to introduce nucleic acids into cells in vitro.
• Diagnostic Assay Development: Employed in the fabrication of biosensors and diagnostic platforms where a stable, functionalized lipid interface is required.
• Cosmetic & Dermal Formulations: Acts as a biocompatible emulsifier and skin-identical lipid for advanced skincare products, enhancing product stability and skin barrier repair.
• Bioconjugation & Surface Modification: The primary amine group on the phosphoethanolamine headgroup provides a site for chemical conjugation with targeting ligands, dyes, or other functional molecules.

Basic Information

Product Name	1,2-Dihexadecanoyl-Rac-Glycero-3-Phosphoethanolamine
CAS No.	5681-36-7
Molecular Formula	C37H74NO8P
Molecular Weight	691.96 g/mol
Synonyms	DPPE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (racemic); 1,2-Dipalmitoylphosphatidylethanolamine; Phosphatidylethanolamine (16:0/16:0); PE(16:0/16:0); Dipalmitoylphosphatidylethanolamine; Dipalmitoyl PE; (Rac)-1,2-Dipalmitoylphosphatidylethanolamine
EINECS	Contact for details

Quality Control

Our 1,2-Dihexadecanoyl-Rac-Glycero-3-Phosphoethanolamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical and life science research. Certificates of Analysis (COA) detailing purity, lipid profile, and critical impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	~190 - 195 °C
Solubility	Soluble in chloroform, methanol; insoluble in water
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines
Microbial Limits	< 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.