Description

N,N'-Diphenylphosphorodiamidic Chloride is a versatile organophosphorus reagent characterized by its reactive P-Cl bond and two phenylamide groups. This compound is crucial for the synthesis of complex phosphoramidates and phosphorodiamidates, serving as a key building block in advanced chemical manufacturing. It is primarily needed by research institutions and industrial producers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel phosphoramidate prodrugs and nucleotide analogs with potential antiviral or anticancer activity.
• Agrochemical Synthesis: Building block for creating advanced insecticides, herbicides, and fungicides that leverage phosphorus chemistry for enhanced efficacy.
• Ligand and Catalyst Preparation: Used to synthesize specialized phosphoramidate ligands for metal complexes in catalytic processes.
• Polymer Modification: Serves as a reactive monomer or cross-linking agent in the production of flame-retardant or specialty polymers.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new reactions in organophosphorus chemistry.
• Peptide and Protein Chemistry: Potential use as a phosphorylating agent for modifying amino acid side chains in biochemical studies.

Basic Information

Product Name	N,N'-Diphenylphosphorodiamidic Chloride
CAS No.	5625-99-0
Molecular Formula	C12H12ClN2OP
Molecular Weight	266.66 g/mol
Synonyms	Diphenylphosphorodiamidic Chloride; Phosphorodiamidic Chloride, N,N'-Diphenyl-; N,N-Diphenylphosphorodiamidic Chloride; Chloro-N,N'-diphenylphosphorodiamidate; P,P-Dichloro-N,N'-diphenylphosphonic Diamide (common misnomer); Phenylphosphorodiamidic Chloride, N,N'-Diphenyl Derivative
EINECS	Contact for details

Quality Control

Our N,N'-Diphenylphosphorodiamidic Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.