Description

4-(1-Piperazinylsulfonyl)Morpholine Hydrochloride is a high-purity, specialized organic building block with a sulfonyl-linked piperazine-morpholine scaffold. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly those targeting neurological disorders or requiring sophisticated heterocyclic architectures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the sulfonyl linker and amine functionalities can impart specific biological activity.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating tool compounds and probes used to study enzyme function and biological pathways.
• Polymer & Material Science: Can be incorporated as a monomer or cross-linking agent to develop polymers with specific thermal or mechanical properties.
• Ligand Development for Catalysis: The nitrogen and oxygen donor atoms make it a candidate for designing novel ligands used in metal-catalyzed reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this precise molecular fragment.

Basic Information

Product Name	4-(1-Piperazinylsulfonyl)Morpholine Hydrochloride
CAS No.	5625-93-4
Molecular Formula	C8H17N3O3S • HCl
Molecular Weight	280.76 g/mol (for free base: 219.30 g/mol)
Synonyms	4-(Piperazine-1-sulfonyl)morpholine hydrochloride; Morpholine, 4-(1-piperazinylsulfonyl)-, hydrochloride; 1-(Morpholinosulfonyl)piperazine hydrochloride; 4-(Piperazin-1-ylsulfonyl)morpholine HCl; 5625-93-4 (CAS); Piperazine, 1-(morpholinosulfonyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-(1-Piperazinylsulfonyl)Morpholine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency meet the exacting standards required for research and development. A detailed Certificate of Analysis (COA) including HPLC purity, NMR confirmation, and residual solvent analysis is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.