Description

(4-Cyanomethyl-Piperazin-1-Yl)-Acetonitrile is a versatile bifunctional nitrile compound featuring a piperazine linker, making it a valuable building block in advanced organic synthesis. Its dual reactive cyano groups allow for selective transformations, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of piperazine-based drug candidates, including kinase inhibitors, receptor antagonists, and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the piperazine moiety contributes to biological activity.
• Ligand and Chelator Preparation: Serves as a starting material for creating complexing agents and ligands used in catalysis and metal ion sequestration.
• Polymer Chemistry: Functions as a monomer or cross-linking agent in the production of specialty polymers and resins with tailored properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and advanced materials.

Basic Information

Item	Details
Product Name	(4-Cyanomethyl-Piperazin-1-Yl)-Acetonitrile
CAS No.	5623-99-4
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	1,4-Piperazinediacetonitrile, dicyanomethylated; 1,4-Bis(cyanomethyl)piperazine; Piperazine-1,4-diacetonitrile; NSC 401123; Bis(cyanomethyl)piperazine; 1,4-Di(cyanomethyl)piperazine; Acetonitrile, (4-cyanomethyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our (4-Cyanomethyl-Piperazin-1-Yl)-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.