Description

1-Piperazinebutanol(6Ci,7Ci,8Ci,9Ci) is a versatile piperazine derivative with a terminal hydroxyl group, serving as a crucial building block in advanced organic synthesis. Its bifunctional nature makes it an essential intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific piperazine-based architectures.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in metal-catalyzed reactions and homogeneous catalysis research.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal or mechanical properties.
• Bioconjugation Chemistry: Utilized in the synthesis of linkers for antibody-drug conjugates (ADCs) and other biopharmaceutical constructs.
• Research & Development: A valuable tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-Piperazinebutanol(6Ci,7Ci,8Ci,9Ci)
CAS No.	5623-92-7
Molecular Formula	C8H18N2O
Molecular Weight	158.24 g/mol
Synonyms	4-(2-Hydroxyethyl)piperazine; 1-(2-Hydroxyethyl)piperazine (common misnomer for related compound, often searched); N-(2-Hydroxyethyl)piperazine; 2-(Piperazin-1-yl)ethanol (isomeric structure); Piperazine, 1-(2-hydroxyethyl)-; UNII-8M5F5O8Y2U; Butanol, 1-piperazinyl-; 1-Piperazineethanol (related base structure)
EINECS	227-056-2

Quality Control

Our 1-Piperazinebutanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and batch-to-batch consistency for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.