Description

Pyridine-2,5-Dicarbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its dual acid chloride functionality, enabling efficient formation of amide and ester bonds under mild conditions. This compound is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing pyridine-based heterocycles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific pyridine-carboxamide structures.
• Ligand and Chelator Production: Serves as a precursor for creating sophisticated polydentate ligands used in catalysis and metal ion sequestration.
• Polymer Chemistry: Employed in the synthesis of functional polymers and polyamides with tailored thermal and mechanical properties.
• Peptide Mimetics & Conjugation: Facilitates the introduction of pyridine motifs into peptide backbones or for bioconjugation applications.
• Material Science Research: Used in developing novel organic frameworks (e.g., MOFs, COFs) and advanced organic electronic materials.

Basic Information

Product Name	Pyridine-2,5-Dicarbonyl Chloride
CAS No.	5620-35-9
Molecular Formula	C7H3Cl2NO2
Molecular Weight	204.01 g/mol
Synonyms	2,5-Pyridinedicarbonyl Dichloride; 2,5-Dicarboxypyridine Dichloride; 2,5-Bis(chlorocarbonyl)pyridine; Pyridine-2,5-dicarboxylic Acid Dichloride; 2,5-Pyridinedicarboxylic Acid Chloride; Isocinchomeronyl Dichloride; Cinchomeronyl Dichloride
EINECS	227-052-5

Quality Control

Our Pyridine-2,5-Dicarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.