Description

Homo-γ-Linolenic Acid (HGLA) is a significant ω-6 polyunsaturated fatty acid (PUFA) with the CAS registry number 5598-38-9. This compound serves as a crucial biochemical intermediate in the biosynthesis of anti-inflammatory eicosanoids and other bioactive lipid mediators. It is essential for research and development in the pharmaceutical, nutraceutical, and advanced cosmetic industries, where its purity and stability are paramount for efficacy and product integrity.

Application

• Pharmaceutical Intermediates: Key precursor for the synthesis of prostaglandins, leukotrienes, and other specialized pro-resolving mediators (SPMs) with targeted anti-inflammatory activity.
• Dietary Supplements & Nutraceuticals: Incorporated into formulations aimed at supporting metabolic health, managing inflammatory conditions, and promoting skin health from within.
• Advanced Cosmetic Actives: Used in high-performance skincare products for its role in supporting skin barrier function, modulating inflammation, and improving skin hydration and elasticity.
• Biochemical & Nutritional Research: Serves as a standard and reagent in studies investigating fatty acid metabolism, lipidomics, and the role of ω-6 fatty acids in human health and disease.
• Cell Culture Media Supplement: Added to specialized media formulations to study lipid signaling pathways and for the production of certain cell-derived therapeutic products.

Basic Information

Item	Details
Product Name	Homo-γ-Linolenic Acid
CAS No.	5598-38-9
Molecular Formula	C20H34O2
Molecular Weight	306.48 g/mol
Synonyms	Homo-γ-linolenic acid; HGLA; all-cis-8,11,14-Eicosatrienoic acid; 20:3 (n-6); Mead acid (Note: Mead acid is an isomer, but often referenced); 8Z,11Z,14Z-Eicosatrienoic acid; (8Z,11Z,14Z)-Icosatrienoic acid; γ-Homolinolenic acid
EINECS	227-006-5

Quality Control

Our Homo-γ-Linolenic Acid is produced and tested under strict quality management systems. Each batch is analyzed to ensure high purity and consistency, with specifications tailored to meet the demands of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with relevant standards for research and ingredient use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below. This product is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (Typical 97-99%)
Peroxide Value	< 5.0 mEq/kg
Heavy Metals (as Pb)	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.