Description

(+/-)-11-Hydroxy-12E,14Z-Eicosadienoic Acid CAS NO 5598-37-8 is a hydroxylated, polyunsaturated eicosadienoic acid derivative, a key intermediate in the study of lipid mediators and eicosanoid biosynthesis. This compound is of significant value for research and development in pharmacology and biochemistry, serving as a crucial building block for synthesizing more complex lipid signaling molecules. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on inflammation, metabolic pathways, and drug discovery.

Application

• Biochemical Research: Critical intermediate for studying eicosanoid biosynthesis pathways, including prostaglandins and leukotrienes.
• Pharmaceutical Development: Used as a synthetic precursor for novel anti-inflammatory and immunomodulatory drug candidates.
• Lipidomics & Metabolomics: Serves as a reference standard or analytical standard in mass spectrometry for identifying and quantifying lipid mediators.
• Cell Signaling Studies: Employed in in vitro and in vivo models to investigate the role of hydroxylated fatty acids in cellular communication.
• Specialty Chemical Synthesis: A versatile chiral building block for the synthesis of complex, biologically active natural product analogs.

Basic Information

Product Name	(+/-)-11-Hydroxy-12E,14Z-Eicosadienoic Acid
CAS No.	5598-37-8
Molecular Formula	C₂₀H₃₄O₃
Molecular Weight	322.48 g/mol
Synonyms	11-Hydroxy-12E,14Z-eicosadienoic acid; (±)-11-Hydroxy-12E,14Z-eicosadienoic acid; 11-Hydroxy-(12E,14Z)-eicosadienoic acid; 11-Hydroxy-12-trans,14-cis-eicosadienoic acid; 11-Hydroxy-12,14-eicosadienoic acid; 11-HEDE; 11-HODE analog; 11-Hydroxy-12,14-docosadienoic acid (common misnomer)
EINECS	Contact for details

Quality Control

Our (+/-)-11-Hydroxy-12E,14Z-Eicosadienoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by GC or titration)
Isomeric Purity (12E,14Z)	≥ 90% (by GC)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.