Description

Glyparamide is a synthetic sulfonylurea compound with significant pharmacological research interest. This high-purity chemical is valued for its role as a key intermediate and reference standard in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in metabolic disorder research and drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel sulfonylurea-based drug candidates.
• Reference Standard: Used as an analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Studies: Employed in in vitro and preclinical studies to investigate mechanisms related to insulin secretion and glucose metabolism.
• Fine Chemical Synthesis: Acts as a building block for the preparation of more complex, target-specific molecules in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for pharmacological and metabolic pathway research.

Basic Information

Product Name	Glyparamide
CAS No.	5581-42-0
Molecular Formula	C₁₈H₂₀N₂O₅S
Molecular Weight	376.43 g/mol
Synonyms	1-(p-[2-(5-Chloro-o-anisamido)ethyl]benzenesulfonyl)-3-cyclohexylurea; Glyparamide; Glypalamide; Glyprolamide; Glipalamide; N-[4-[β-(3-Cyclohexylureido)sulfonyl]phenethyl]-5-chloro-2-methoxybenzamide; HB 419 (historical code); CAS 5581-42-0
EINECS	Contact for details

Quality Control

Our Glyparamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.