Description

1-tert-Butyl-4-Chloro-Piperidine is a high-purity, functionalized piperidine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, offering a unique sterically hindered tert-butyl group and a reactive chloro substituent for further functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the piperidine scaffold contributes to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D Laboratories: A valuable reagent for methodological studies and exploring new chemical reactions in organic chemistry.

Basic Information

Product Name	1-tert-Butyl-4-Chloro-Piperidine
CAS No.	5570-81-0
Molecular Formula	C9H18ClN
Molecular Weight	175.70 g/mol
Synonyms	4-Chloro-1-tert-butylpiperidine; 1-(1,1-Dimethylethyl)-4-chloropiperidine; 4-Chloro-1-(tert-butyl)piperidine; N-tert-Butyl-4-chloropiperidine; tert-Butyl 4-chloropiperidine-1-carboxylate (related ester); 4-Chloro-N-tert-butylpiperidine; Piperidine, 4-chloro-1-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-4-Chloro-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.