Description

(R)-n-4-Benzyl-2-Phenylpiperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile and valuable chiral building block for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce enantioselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for constructing complex molecular architectures in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the synthesis of chiral active ingredients for crop protection products.
• Fine Chemical Synthesis: A building block for creating specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic Research: Used in universities and research institutes for methodological studies in organic and organometallic chemistry.

Basic Information

Product Name	(R)-n-4-Benzyl-2-Phenylpiperazine
CAS No.	5368-32-1
Molecular Formula	C₁₇H₂₀N₂
Molecular Weight	252.36 g/mol
Synonyms	(R)-1-Benzyl-4-phenylpiperazine; (R)-N-Benzyl-2-phenylpiperazine; (R)-4-Benzyl-2-phenylpiperazine; (R)-N-Benzyl-N'-phenylpiperazine; (R)-BPP; (R)-1-Phenyl-4-benzylpiperazine; (R)-enantiomer of 1-Benzyl-4-phenylpiperazine; (2R)-1-Benzyl-4-phenylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-n-4-Benzyl-2-Phenylpiperazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.