Description

2-Acetoxydodecahydro-8-Hydroxy-1B,7-Dimethyl-3-Methyleneoxireno[2,3]Azuleno[6,5-B]Furan-4-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This compound matters as a high-value advanced pharmaceutical intermediate or research chemical, offering a sophisticated structural framework for drug discovery and synthesis. It is primarily needed by R&D teams and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic agents and specialty products.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting inflammation or cancer.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold in structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total or semi-synthesis of complex natural products with sesquiterpene backbones.
• Biochemical Research: Employed in studies investigating the biological mechanisms and pathways of sesquiterpene lactones.
• Agrochemical Development: Potential use as an intermediate for creating new plant protection agents with unique modes of action.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals requiring a high degree of stereochemical and functional complexity.

Basic Information

Product Name	2-Acetoxydodecahydro-8-Hydroxy-1B,7-Dimethyl-3-Methyleneoxireno[2,3]Azuleno[6,5-B]Furan-4-One
CAS No.	5257-99-8
Molecular Formula	C19H26O6
Molecular Weight	350.41 g/mol
Synonyms	8-Hydroxy-1B,7-dimethyl-3-methylenexireno[2,3]azuleno[6,5-b]furan-4-one, 2-acetoxydodecahydro-; 2-Acetoxydodecahydro-8-hydroxy-1B,7-dimethyl-3-methylenexireno[2,3]azuleno[6,5-b]furan-4-one; Parthenolide acetate derivative; Sesquiterpene lactone acetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Acetoxydodecahydro-8-Hydroxy-1B,7-Dimethyl-3-Methyleneoxireno[2,3]Azuleno[6,5-B]Furan-4-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.