Description

(4Alpha,4Abeta,8Aalpha)-Octahydro-4,8A-Dimethyl-4A(2H)-Naphthol is a high-purity, stereochemically defined decalin derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its rigid, fused-ring structure and specific stereochemistry make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty fragrance industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of steroidal analogs, terpenoid-based therapeutics, and other bioactive molecules requiring specific spatial orientation.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its decalin core contributes to stability and biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthetic musks, amber notes, and other complex odorants in high-value perfumery.
• Material Science Research: Acts as a monomer or building block for novel polymers and liquid crystals with specific thermal and optical properties.
• Catalyst & Ligand Development: The functional groups and stereocenters provide a platform for designing novel asymmetric catalysts and chiral ligands.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(4Alpha,4Abeta,8Aalpha)-Octahydro-4,8A-Dimethyl-4A(2H)-Naphthol
CAS No.	5173-69-3
Molecular Formula	C12H22O
Molecular Weight	182.30 g/mol
Synonyms	4a,8a-Dimethyl-decahydro-2-naphthol; 4,8a-Dimethyl-decahydro-2(1H)-naphthalenone (tautomer); 4,8a-Dimethylperhydronaphthalen-2-ol; 4,8a-Dimethyl-decahydronaphthalen-2-ol; 4,8a-Dimethyl-2-decalol; 4,8a-Dimethyl-trans-decahydro-2-naphthol (stereoisomer); Octahydro-4,8a-dimethyl-4a(2H)-naphthalenol
EINECS	Contact for details

Quality Control

Our (4Alpha,4Abeta,8Aalpha)-Octahydro-4,8A-Dimethyl-4A(2H)-Naphthol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.