Description

Flurbiprofen is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the phenylalkanoic acid class, widely recognized for its anti-inflammatory, analgesic, and antipyretic properties. Its primary commercial value lies in its effectiveness as an active pharmaceutical ingredient (API) for treating pain and inflammation associated with conditions like arthritis and post-operative recovery. This compound is essential for pharmaceutical manufacturers, research institutions, and chemical distributors serving the global healthcare sector. Flurbiprofen CAS NO 5104-49-4 is a key building block in the production of various therapeutic formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter oral tablets, capsules, and topical gels for pain and inflammation management.
• Ophthalmic Solutions: Formulation into eye drops for the treatment of ocular inflammation following cataract surgery or other procedures.
• Veterinary Medicine: Incorporation into veterinary pharmaceuticals for managing pain and inflammation in animals.
• Research & Development: Serves as a critical reference standard and starting material in pharmacological research and the development of new NSAID derivatives.
• Analytical Chemistry: Used as a certified reference material (CRM) in quality control laboratories for method validation and calibration.
• Dental Applications: Component in formulations for post-dental procedure pain relief.

Basic Information

Product Name	Flurbiprofen
CAS No.	5104-49-4
Molecular Formula	C15H13FO2
Molecular Weight	244.26 g/mol
Synonyms	(±)-2-Fluoro-α-methyl-4-biphenylacetic acid; (±)-Flurbiprofen; Ansaid; Froben; Cebutid; Flugalin; 2-(2-Fluoro-4-biphenylyl)propionic acid; 2-(3-Fluoro-4-phenylphenyl)propanoic acid
EINECS	225-819-6

Quality Control

Our Flurbiprofen is manufactured under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. Each batch is tested against rigorous specifications, including identity, purity, and impurity profiles, with methods aligned to major pharmacopoeias such as USP and EP. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all test results to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Optical Rotation	-0.10° to +0.10° (c=1 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.