Description

(3As,6Aβ,9Bβ)-3A,4,5,6,6A,7,8,9,9A,9B-Decahydro-8β,9β-Dihydroxy-6α,9Aα-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a key building block for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation and other biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or starting material for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Natural Product Synthesis: Serves as a synthetic target or intermediate in the total synthesis of complex natural products with sesquiterpene lactone cores.
• Biochemical Research: Employed in studies investigating the biological mechanisms and interactions of sesquiterpene lactones.
• Agrochemical Development: Potential use as an intermediate in the research and development of new crop protection agents.
• Fine Chemical Synthesis: A valuable chiral building block for the production of specialty chemicals and advanced materials.

Basic Information

Product Name	(3As,6Aβ,9Bβ)-3A,4,5,6,6A,7,8,9,9A,9B-Decahydro-8β,9β-Dihydroxy-6α,9Aα-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One
CAS No.	5090-67-5
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	8β,9β-Dihydroxy-6α,9aα-dimethyl-3-methylenedecahydroazuleno[4,5-b]furan-2(3H)-one; Alantolactone Isomer; Isoalantolactone; (3aR,6aS,9aR,9bS)-3a,4,5,6,6a,7,8,9,9a,9b-Decahydro-8,9-dihydroxy-6a,9a-dimethyl-3-methylenenaphtho[2,1-b]furan-2(1H)-one; 6α,9aα-Dimethyl-3-methylenedecahydroazuleno[4,5-b]furan-2,8,9(3H,3aH)-trione (hydrogenated derivative reference); Helenin derivative; Sesquiterpene Lactone Derivative
EINECS	Contact for details

Quality Control

Our (3As,6Aβ,9Bβ)-3A,4,5,6,6A,7,8,9,9A,9B-Decahydro-8β,9β-Dihydroxy-6α,9Aα-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.