Description

4-Carbamyl-1-Piperazinecarboxylic Acid Benzyl Ester is a versatile and high-value piperazine derivative used as a critical building block in advanced organic synthesis. Its structure makes it an essential intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the piperazine scaffold for biological activity.
• Fine Chemical Production: Serves as a precursor for the manufacture of complex specialty chemicals and ligands used in catalysis.
• Academic & Industrial Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetic Chemistry: Utilized in the design and synthesis of peptide analogs and conformationally restricted scaffolds.

Basic Information

Product Name	4-Carbamyl-1-Piperazinecarboxylic Acid Benzyl Ester
CAS No.	588-88-5
Molecular Formula	C13H17N3O3
Molecular Weight	263.29 g/mol
Synonyms	1-Benzyl 4-Carbamoylpiperazine-1-carboxylate; Benzyl 4-Carbamoylpiperazine-1-carboxylate; 1-Carbobenzyloxy-4-carbamoylpiperazine; 1-(Benzyloxycarbonyl)-4-carbamoylpiperazine; 4-Carbamoyl-1-(benzyloxycarbonyl)piperazine; Z-Piperazine-4-carboxamide; 1-Piperazinecarboxylic acid, 4-(aminocarbonyl)-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-Carbamyl-1-Piperazinecarboxylic Acid Benzyl Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and cGMP manufacturing applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.