Description

Diloxanide CAS NO 579-38-4 is a synthetic chemical compound primarily recognized for its potent anti-amoebic properties. It serves as a critical active pharmaceutical ingredient (API) in the treatment of intestinal protozoal infections, offering targeted therapeutic action. This compound is essential for pharmaceutical manufacturers developing formulations for anti-parasitic and anti-infective medications, particularly in regions where such infections are endemic.

Application

• Pharmaceutical API: Primary use as the active ingredient in anti-amoebic medications for treating intestinal infections like amebiasis.
• Veterinary Medicine: Formulation component in anti-parasitic treatments for livestock and companion animals.
• Research & Development: Key reference standard and intermediate in pharmacological and parasitological research.
• Generic Drug Manufacturing: Sourcing for cost-effective production of generic anti-protozoal drugs.
• Combination Therapies: Used in fixed-dose combination drugs alongside other anti-infective agents for broad-spectrum treatment.

Basic Information

Product Name	Diloxanide
CAS No.	579-38-4
Molecular Formula	C14H11Cl2NO3
Molecular Weight	312.15 g/mol
Synonyms	Diloxanide Furoate (ester form); Diloxanide Furoate API; 2,2-Dichloro-4'-hydroxy-N-methylacetanilide; 4-(N-Methylacetamido)-2,2-dichlorophenyl acetate; Entamide; Furanide; Furodiloxan; NSC 527986; CAS 3736-81-0 (for the furoate salt)
EINECS	209-437-0

Quality Control

Our Diloxanide is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via validated methods such as HPLC. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request. We support customers requiring material aligned with ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.