Description

γ-Hydroxyphenylbutazone CAS NO 568-76-3 is a hydroxylated derivative of the anti-inflammatory drug phenylbutazone, representing a key intermediate in pharmaceutical research and development. This compound is of significant interest for its potential role in studying metabolic pathways and developing novel therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical and life sciences sectors. Its precise chemical structure makes it a valuable building block for synthesizing and investigating new chemical entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel anti-inflammatory and analgesic drug candidates.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and metabolism studies related to phenylbutazone.
• Biochemical Research: Employed in laboratory investigations to study enzyme inhibition, metabolic pathways, and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Development: Acts as a starting material or intermediate for the development of new API formulations.
• Veterinary Medicine Research: Applied in research for developing therapeutic agents in veterinary sciences.

Basic Information

Product Name	γ-Hydroxyphenylbutazone
CAS No.	568-76-3
Molecular Formula	C19H20N2O3
Molecular Weight	324.38 g/mol
Synonyms	4-Hydroxyphenylbutazone; 1,2-Diphenyl-4-(4-hydroxyphenyl)-3,5-pyrazolidinedione; γ-Hydroxyphenylbutazone; GHPB; Oxyphenbutazone Metabolite; 4'-Hydroxyphenylbutazone; 1,2-Diphenyl-4-(4-hydroxyphenyl)-3,5-dioxopyrazolidine
EINECS	Contact for details

Quality Control

Our γ-Hydroxyphenylbutazone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing specific results for each parameter is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect the light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.