Description

5-Cholestene-3 Beta,12 α-Diol is a high-purity sterol derivative, a key intermediate in the synthesis of complex steroid hormones and pharmaceutical actives. Its defined stereochemistry at the 3-beta and 12-alpha positions makes it a valuable chiral building block for research and development in medicinal chemistry. This compound is essential for laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise steroid scaffolds.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of specific steroid-based drugs and therapeutic agents.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies, enzyme inhibition assays, and steroid receptor research.
• Fine Chemical Synthesis: Serves as a chiral template for constructing more complex steroidal molecules with targeted biological activity.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of sterol-related products.
• Nutraceutical Development: Investigated for potential use in the development of advanced dietary supplements targeting specific metabolic functions.

Basic Information

Product Name	5-Cholestene-3 Beta,12 α-Diol
CAS No.	566-46-1
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.66 g/mol
Synonyms	3β,12α-Dihydroxycholest-5-ene; 12α-Hydroxycholesterol; (3β,12α)-Cholest-5-ene-3,12-diol; 5-Cholestene-3β,12α-diol; 12α-Hydroxy-5-cholesten-3β-ol
EINECS	209-295-1

Quality Control

Our 5-Cholestene-3 Beta,12 α-Diol is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity reference materials and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.