Description

Allopregnane-3Beta,21-Diol-11,20-Dione is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of advanced corticosteroid and other steroidal APIs. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for drug discovery and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of corticosteroid drugs and other steroidal active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and steroid hormone research.
• Organic Synthesis: Employed as a versatile chiral building block for constructing complex steroidal molecules in medicinal chemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	Allopregnane-3Beta,21-Diol-11,20-Dione
CAS No.	566-02-9
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	11β,21-Dihydroxy-3,20-diketo-5β-pregnane; 11β,21-Dihydroxypregnane-3,20-dione; 5β-Pregnane-3β,21-diol-11,20-dione; 3β,21-Dihydroxy-5β-pregnane-11,20-dione; 21-Hydroxy-11,20-dioxo-5β-pregnan-3β-ol; Allopregnanediolone; A key metabolite/allopregnanolone precursor.
EINECS	Contact for details

Quality Control

Our Allopregnane-3Beta,21-Diol-11,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.