Description

Strophanthidol is a key cardenolide aglycone derived from natural sources, serving as a critical intermediate and reference standard in pharmaceutical research and development. Its significance lies in its structural relationship to potent cardiac glycosides, making it invaluable for studying heart failure therapeutics and synthesizing novel bioactive compounds. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors who require reliable, well-characterized building blocks for drug discovery and analytical applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and quantification of cardiac glycosides in raw materials and finished drug products.
• Drug Discovery Intermediate: Serves as a crucial synthetic precursor for the research and development of novel cardiotonic agents and other therapeutic molecules.
• Biochemical Research: Employed in pharmacological studies to investigate the structure-activity relationships (SAR) of digitalis-like compounds and their mechanisms of action on sodium-potassium ATPase.
• Analytical Chemistry: Utilized as an internal standard or calibrant in chromatographic methods (HPLC, LC-MS) for the analysis of plant extracts and biological samples.
• Fine Chemical Synthesis: Acts as a specialized building block for the semi-synthesis of complex natural products and their derivatives.

Basic Information

Product Name	Strophanthidol
CAS No.	560-54-3
Molecular Formula	C₂₃H₃₂O₅
Molecular Weight	388.50 g/mol
Synonyms	3β,5,14-Trihydroxy-19-oxo-5β-card-20(22)-enolide; Strophanthidin 3β-ol; 3β-Hydroxystrophanthidin; (3β,5β)-3,5,14-Trihydroxy-19-oxocard-20(22)-enolide; NSC 406290; Strophanthidol aglycone; Strophanthidine alcohol
EINECS	Contact for details

Quality Control

Every batch of our Strophanthidol is produced and tested under a strict quality management system to ensure identity, purity, and consistency. We provide comprehensive analytical data including HPLC purity, residual solvent analysis, and confirmation of structure by spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is supplied with each shipment, supporting compliance in GMP-oriented research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.