Description

Acetyl Fluoride is a highly reactive and versatile fluorinating agent and acylating intermediate. Its primary value lies in its ability to efficiently introduce fluorine atoms or acetyl groups into complex organic molecules, a critical step in the synthesis of advanced materials and pharmaceuticals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries, where precise fluorination is required to modify the biological activity and physical properties of target compounds.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of fluorinated active pharmaceutical ingredients (APIs) to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where fluorination improves efficacy and environmental profile.
• Liquid Crystal & Polymer Chemistry: Acts as a building block for fluorinated monomers and polymers, imparting unique thermal, chemical, and surface properties.
• Organic Synthesis Reagent: Employed as a selective fluorinating and acylating agent in complex multi-step laboratory and pilot-scale reactions.
• Electrolyte Additive Research: Investigated for use in advanced battery systems to improve electrolyte stability and performance.
• Refrigerant & Propellant Precursor: Serves as an intermediate in the manufacturing of next-generation fluorinated greenhouse gas alternatives.

Basic Information

Item	Details
Product Name	Acetyl Fluoride
CAS No.	557-99-3
Molecular Formula	C2H3FO
Molecular Weight	62.04 g/mol
Synonyms	Acetic fluoride; Ethanoyl fluoride; Fluoromethyl ketone; Acetylfluorid; Fluoroacetyl; Methanecarbonyl fluoride; Acetylfluorure (French); Acetilfluoruro (Spanish)
EINECS	209-185-2

Quality Control

Our Acetyl Fluoride is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and NMR spectroscopy, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated area, away from heat sources and incompatible materials such as strong bases, alcohols, and oxidizing agents. Recommended storage temperature is 2-8°C for extended stability. Handle under an inert atmosphere (e.g., nitrogen or argon) in a fume hood to minimize moisture exposure and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acetic Acid (GC)	≤ 1.0%
Hydrofluoric Acid (Titration)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.