Description

1,4:3,6-Dianhydro-D-Mannitol Dinitrate is a specialized organic nitrate compound of significant interest in advanced chemical synthesis and pharmaceutical research. This high-purity intermediate is valued for its unique bicyclic structure and reactivity, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of cardiovascular and other therapeutic agents.
• Energetic Materials Research: Used in the study and development of specialized propellants and explosives formulations.
• Organic Synthesis: Serves as a versatile chiral precursor for constructing complex molecular architectures in fine chemical production.
• Agrochemical Development: Employed in the research phase for creating novel active ingredients with specific biological activity.
• Academic & Industrial R&D: A critical reagent for methodological studies in nitration chemistry and carbohydrate derivative applications.

Basic Information

Product Name	1,4:3,6-Dianhydro-D-Mannitol Dinitrate
CAS No.	551-43-9
Molecular Formula	C6H8N2O8
Molecular Weight	236.14 g/mol
Synonyms	Isosorbide Dinitrate; 1,4:3,6-Dianhydro-D-glucitol Dinitrate; D-Isosorbide Dinitrate; ISDN; Sorbide Nitrate; D-Glucitol, 1,4:3,6-dianhydro-, dinitrate; (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl dinitrate
EINECS	209-001-6

Quality Control

Our 1,4:3,6-Dianhydro-D-Mannitol Dinitrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). The COA includes data for identity, assay, impurity profile, and residual solvents, meeting the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture sources. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.