Description

Girard's Reagent D is a specialized hydrazine-based derivatization agent, widely recognized for its high reactivity and selectivity towards carbonyl compounds. Its primary value lies in its ability to selectively isolate and purify ketones and aldehydes from complex mixtures, a critical step in analytical and synthetic workflows. This reagent is essential for researchers and quality control laboratories in the pharmaceutical, fragrance, and food chemistry industries, where precise analysis and purification of carbonyl-containing molecules are paramount.

Application

• Analytical Chemistry: Selective derivatization of ketosteroids and other carbonyl compounds for analysis by HPLC, GC-MS, or spectrophotometry.
• Pharmaceutical Purification: Isolation and purification of active pharmaceutical ingredients (APIs) and intermediates containing aldehyde or ketone functional groups.
• Fragrance & Flavor Analysis: Extraction and concentration of key carbonyl-based aroma compounds from natural products for identification and quality assessment.
• Biomarker Research: Derivatization of endogenous aldehydes (e.g., from lipid peroxidation) in biological samples for sensitive detection in metabolomic studies.
• Organic Synthesis: Used as a protecting group or as a reagent in the synthesis of hydrazone derivatives for further chemical transformations.
• Food Safety Testing: Employed in methods to detect and quantify undesirable carbonyl compounds, such as certain mycotoxins or process contaminants.

Basic Information

Product Name	Girard's Reagent D
CAS No.	539-64-0
Molecular Formula	C5H14ClN3O
Molecular Weight	167.64 g/mol
Synonyms	1-(Carboxymethyl)pyridinium chloride hydrazide; (Carboxymethyl)trimethylammonium chloride hydrazide; Girard-D Reagent; Girard's D Reagent; Girard D; Trimethylammonioacetohydrazide chloride; Acetohydrazide trimethylammonium chloride; [2-(Hydrazinecarbonyl)ethyl]trimethylammonium chloride
EINECS	208-719-7

Quality Control

Our Girard's Reagent D is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance, meeting the exacting standards required for research and analytical applications. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light may affect its stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	190 - 195 °C (dec.)
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.