Description

Shikonin is a highly bioactive naphthoquinone pigment naturally derived from the roots of *Lithospermum erythrorhizon* and related species. This compound is valued for its potent anti-inflammatory, antimicrobial, and antitumor properties, making it a critical intermediate for advanced research and product development. It serves key roles in the pharmaceutical, cosmetic, and nutraceutical industries, particularly in formulations targeting skin health, wound healing, and novel therapeutic pathways.

Application

• Pharmaceutical Research & Development: As a lead compound or reference standard in studies for anti-cancer, anti-inflammatory, and antimicrobial drug discovery.
• Cosmetic & Skincare Formulations: Incorporated into creams, serums, and ointments for its skin-soothing, wound-healing, and anti-aging benefits.
• Natural Colorant & Dye: Used as a source of deep red-purple pigment in high-value applications such as natural textiles and cosmetics.
• Nutraceuticals & Dietary Supplements: Employed as an active ingredient in supplements focused on immune support and antioxidant protection.
• Biochemical & Cell Biology Research: Utilized as a tool compound to study cellular signaling pathways, including apoptosis and NF-κB inhibition.
• Agricultural Applications: Investigated for its potential as a natural antifungal or antibacterial agent in crop protection.

Basic Information

Product Name	Shikonin
CAS No.	517-89-5
Molecular Formula	C₁₆H₁₆O₅
Molecular Weight	288.29 g/mol
Synonyms	(-)-Shikonin; Shikonine; Alkannin enantiomer; Isoarnebin 4; NSC 143491; 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-naphthoquinone; (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthalenedione
EINECS	208-234-7

Quality Control

Our Shikonin is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Dark red to purple crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.