Description

Sanshool is a bioactive alkylamide compound, specifically a mixture of hydroxy-α-sanshool isomers, known for its unique tingling and numbing sensory properties. This compound matters for its ability to interact with specific receptors in sensory neurons, making it a valuable tool for research and product development in sensory modulation. Industries that need Sanshool CAS NO 504-97-2 include flavor and fragrance, nutraceutical, cosmetic, and pharmaceutical research, where it is used to create novel sensory experiences or study neurological pathways.

Application

• Flavor & Fragrance Industry: Used as a key ingredient to impart a characteristic tingling, warming, or numbing sensation in oral care products, confectionery, and specialty beverages.
• Cosmetic & Personal Care: Incorporated into formulations for lip plumpers, anti-aging creams, and topical analgesics to provide a mild, temporary sensory effect that enhances product perception.
• Nutraceutical & Dietary Supplements: Serves as an active component in supplements aimed at promoting oral health or providing a unique sensory trigger.
• Pharmaceutical Research: Employed as a reference standard or active pharmaceutical ingredient (API) in studies targeting TRPV1 and other ion channels involved in pain and temperature sensation.
• Food Technology: Applied in experimental food products to create innovative mouthfeel and flavor-enhancing effects.
• Neurological & Biological Studies: Utilized in vitro and in vivo as a chemical probe to investigate the mechanisms of somatosensation and neuronal excitation.

Basic Information

Product Name	Sanshool
CAS No.	504-97-2
Molecular Formula	C16H25NO
Molecular Weight	247.38 g/mol
Synonyms	Hydroxy-α-sanshool; (2E,6E,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide; Sanshool; α-Hydroxysanshool; Spilanthol (related compound, often used interchangeably); Alkylamide from Zanthoxylum; Jambu oleoresin constituent
EINECS	Contact for details

Quality Control

Our Sanshool is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is analyzed using validated methods including HPLC and GC to confirm identity, potency, and the absence of significant impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support compliance requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Pale yellow to amber viscous liquid or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (Total Sanshool isomers)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.