Description

Diphosgene is a versatile and highly reactive chemical reagent widely used as a phosgene substitute in organic synthesis. Its primary value lies in its ability to safely and efficiently introduce carbonyl and chloroformyl groups, making it indispensable for constructing complex molecular architectures. This compound is critical for manufacturers and research institutions in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for producing active pharmaceutical ingredients (APIs), including isocyanates, carbamoyl chlorides, and carbonates.
• Agrochemical Production: Used in the manufacture of pesticides, herbicides, and fungicides requiring carbonyl chloride functionalities.
• Polymer & Resin Chemistry: Employed in the synthesis of polycarbonates, polyurethanes, and other specialty polymers.
• Organic Synthesis Reagent: Facilitates chlorination, carbonylation, and dehydration reactions under controlled conditions.
• Peptide Coupling Agent: Acts as a condensing agent for forming peptide bonds in laboratory and process-scale synthesis.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in novel compound discovery and process optimization.

Basic Information

Product Name	Diphosgene
CAS No.	503-38-8
Molecular Formula	C2Cl4O2
Molecular Weight	197.83 g/mol
Synonyms	Trichloromethyl Chloroformate; Triphosgene (Note: Triphosgene is a related but distinct compound, often searched together); Bis(trichloromethyl) Carbonate (common misnomer); Chloroformic Acid Trichloromethyl Ester; TCBC; Diphosgene Gas (when volatilized)
EINECS	207-965-9

Quality Control

Our Diphosgene is manufactured under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by titration and impurity profile analysis via gas chromatography (GC). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong bases, amines, and alcohols. Due to its nature as a strong acid/organic solvent and highly volatile compound, containers must be kept tightly sealed and handled with appropriate engineering controls to prevent vapor release. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0 %
Density (at 20°C)	1.62 - 1.65 g/mL
Boiling Point	128°C
Related Impurities (GC)	≤ 2.0 % total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.