Description

Tolazoline is a potent imidazoline derivative and non-selective α-adrenergic receptor antagonist. This compound is of significant commercial and research interest due to its vasodilatory properties and its role as a key intermediate in pharmaceutical synthesis. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, agrochemical, and life science sectors for the development of active pharmaceutical ingredients (APIs) and specialized chemical products.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of vasodilator drugs and other therapeutic agents targeting the cardiovascular system.
• Research Chemical: Used in biochemical and pharmacological research to study α-adrenergic receptor mechanisms and vascular physiology.
• Agrochemical Synthesis: Serves as a precursor or intermediate in the development of certain pesticides and plant growth regulators.
• Veterinary Medicine: Employed in formulations for the treatment of pulmonary hypertension in animals, particularly in equine medicine.
• Diagnostic Agent: Historically used in diagnostic tests for peripheral vascular disorders.
• Chemical Standard: Supplied as a high-purity reference standard for analytical testing and quality control laboratories.

Basic Information

Product Name	Tolazoline
CAS No.	59-98-3
Molecular Formula	C10H12N2
Molecular Weight	160.22 g/mol
Synonyms	2-Benzyl-2-imidazoline; Priscol; Priscoline; Tolazoline Hydrochloride (salt form); Benzazoline; 2-(Benzyl)imidazoline; 4,5-Dihydro-2-(phenylmethyl)-1H-imidazole; Vasodil
EINECS	200-447-1

Quality Control

Our Tolazoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets exacting standards for pharmaceutical and research use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.