Description

Papaverine Hydrochloride is a pharmaceutical-grade alkaloid salt widely recognized for its potent smooth muscle relaxant properties. This high-purity compound is essential for research and development, as well as the manufacturing of critical therapeutic agents. It serves as a key active pharmaceutical ingredient (API) and intermediate for suppliers targeting the pharmaceutical, biotechnology, and advanced chemical synthesis sectors globally.

Application

• Pharmaceutical API: Primary use as an active ingredient in formulations for treating vasospasm, cerebral ischemia, and certain cardiac conditions.
• Biomedical Research: Critical tool compound for in vitro and in vivo studies investigating smooth muscle physiology, vasodilation mechanisms, and calcium channel blockade.
• Chemical Synthesis: Serves as a sophisticated intermediate or starting material for the synthesis of more complex pharmaceutical derivatives and analogs.
• Reference Standard: Used in analytical laboratories as a high-purity standard for quality control (QC) and assurance (QA) testing via HPLC, GC, or spectroscopy.
• Veterinary Medicine: Employed in veterinary pharmaceuticals for its spasmolytic effects in animals.

Basic Information

Product Name	Papaverine Hydrochloride
CAS No.	58-74-2
Molecular Formula	C20H21NO4 · HCl
Molecular Weight	375.85 g/mol
Synonyms	Papaverine HCl; 6,7-Dimethoxy-1-veratrylisoquinoline hydrochloride; Papaverinium chloride; Cerespan; Pavabid; (1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline) hydrochloride; Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-, hydrochloride
EINECS	200-397-6

Quality Control

Our Papaverine Hydrochloride is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards, potentially including compliance with USP, EP, or customer-specific monographs. Comprehensive testing covers identity, assay, purity, and specified impurities. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.