Description

Hexamethonium Bromide is a quaternary ammonium salt widely recognized for its potent ganglionic blocking activity. This compound is a crucial research-grade chemical for investigating autonomic nervous system pharmacology and serves as a key reference standard in analytical chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and diagnostic reagents.

Application

• Pharmacological Research: As a classic nicotinic acetylcholine receptor (nAChR) antagonist for studying ganglionic transmission and autonomic nervous system function.
• Reference Standard: Used in analytical methods development and validation for quality control in pharmaceutical manufacturing.
• Biochemical Studies: Employed in in vitro and ex vivo experiments to block neuronal signaling pathways.
• Fine Chemical Synthesis: Serves as a building block or intermediate in the synthesis of more complex quaternary ammonium compounds.
• Diagnostic Reagents: Potential component in specialized diagnostic kits for neurological research applications.

Basic Information

Product Name	Hexamethonium Bromide
CAS No.	55-97-0
Molecular Formula	C12H30Br2N2
Molecular Weight	362.19 g/mol
Synonyms	Hexamethonium Dibromide; Hexamethylene-1,6-bis(trimethylammonium) Bromide; 1,6-Hexanediylbis(trimethylammonium) Bromide; Esametonio Bromuro; Hexametonium Bromide; NSC 7571; Hexamethonium Bromide Salt
EINECS	200-252-0

Quality Control

Our Hexamethonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.