Description

1,1-Dimethyl-4-Phenylpiperazinium Iodide is a quaternary ammonium salt with significant biological activity, primarily utilized as a research chemical and pharmaceutical intermediate. Its value lies in its role as a potent and selective ganglionic blocking agent, making it a critical tool for neurological and pharmacological studies. This compound is essential for researchers in academic institutions, pharmaceutical R&D laboratories, and contract research organizations (CROs) focused on autonomic nervous system function and drug discovery.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating ganglionic neurotransmission and nicotinic acetylcholine receptors.
• Neuroscience Tool Compound: Employed in vitro and in vivo to block autonomic ganglia, aiding in the mapping of neural pathways and understanding cardiovascular control.
• Pharmaceutical Intermediate: Serves as a key synthetic building block in the development of novel therapeutic agents targeting the nervous system.
• Biochemical Assay Development: Utilized in the development and validation of high-throughput screening assays for drug discovery programs.
• Academic Teaching & Reference: Provides a classic example of a ganglionic blocker in university-level pharmacology and medicinal chemistry courses.
• Toxicology Studies: Applied in research to understand the effects and mechanisms of ganglionic blocking agents.

Basic Information

Product Name	1,1-Dimethyl-4-Phenylpiperazinium Iodide
CAS No.	54-77-3
Molecular Formula	C12H19IN2
Molecular Weight	318.20 g/mol
Synonyms	DMPP Iodide; 1,1-Dimethyl-4-phenylpiperazin-1-ium iodide; N,N-Dimethyl-N'-phenylpiperazinium iodide; Phenylpiperazinium iodide; Ganglionic Blocking Agent DMPP; NSC 169865; 4-Phenyl-1,1-dimethylpiperazinium iodide
EINECS	200-208-6

Quality Control

Our 1,1-Dimethyl-4-Phenylpiperazinium Iodide is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and loss on drying to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.