Description

Pyrazinecarboxamide, 3,4-Dihydro-3-Oxo-4-(2,3,5-Tri-o-Acetyl-β-D-Ribofuranosyl)- (9Ci) is a sophisticated nucleoside analog derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its primary value lies in enabling the research and development of novel pharmaceutical compounds, particularly in the fields of antiviral and anticancer therapeutics. This high-purity building block is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical synthesis who require reliable, well-characterized intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting viral polymerases or cellular enzymes.
• Process Chemistry Development: Serves as a critical intermediate for scaling up the production of active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition and metabolic pathways involving nucleotide analogs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for research purposes.

Basic Information

Product Name	Pyrazinecarboxamide, 3,4-Dihydro-3-Oxo-4-(2,3,5-Tri-o-Acetyl-β-D-Ribofuranosyl)- (9Ci)
CAS No.	499785-81-8
Molecular Formula	C16H19N3O9
Molecular Weight	397.34 g/mol
Synonyms	4-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-3,4-dihydro-3-oxopyrazine-2-carboxamide; 3-Oxo-4-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide; 4-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-3-oxo-3,4-dihydropyrazine-2-carboxamide; Acetylated Ribofuranosyl Pyrazinecarboxamide Derivative; Nucleoside Analog Intermediate; 499785-81-8; Pyrazine-2-carboxamide, 3,4-dihydro-3-oxo-4-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-
EINECS	Contact for details

Quality Control

Our Pyrazinecarboxamide, 3,4-Dihydro-3-Oxo-4-(2,3,5-Tri-o-Acetyl-β-D-Ribofuranosyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.