Description

2-Piperazineacetic Acid, 5-(2-Aminoethyl)-3,6-Dioxo-, (2S,5R)- (9Ci) is a high-purity, stereochemically defined piperazine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a sophisticated chiral intermediate, enabling the development of complex molecules with precise spatial configurations. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Synthesis: Used to construct constrained peptide backbones and novel amino acid analogs for drug discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts in asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Advanced Material Science: Potential monomer or cross-linking agent for developing specialty polymers with unique functional properties.

Basic Information

Product Name	2-Piperazineacetic Acid, 5-(2-Aminoethyl)-3,6-Dioxo-, (2S,5R)- (9Ci)
CAS No.	499775-01-8
Molecular Formula	C8H15N3O4
Molecular Weight	217.22 g/mol
Synonyms	(2S,5R)-5-(2-Aminoethyl)-3,6-dioxopiperazine-2-acetic acid; (2S,5R)-2-(5-(2-Aminoethyl)-3,6-dioxopiperazin-2-yl)acetic acid; 2-Piperazineacetic acid, 5-(2-aminoethyl)-3,6-dioxo-, (2S,5R)-; (2S,5R)-5-(2-Aminoethyl)-3,6-dioxopiperazine-2-carboxylic acid (tautomeric form); 499775-01-8; (2S,5R)-AEDA; Chiral Dioxopiperazine Acetic Acid Derivative
EINECS	Contact for details

Quality Control

Our 2-Piperazineacetic Acid, 5-(2-Aminoethyl)-3,6-Dioxo-, (2S,5R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S,5R)-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.