Description

4H-1,3-Benzodioxine-7-Carbonyl Chloride, 97% is a high-purity, reactive organic intermediate of significant value in advanced chemical synthesis. Its core utility lies in its carbonyl chloride functional group, which serves as a versatile building block for constructing more complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce the benzodioxine moiety into target molecules, a structure known for conferring specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzodioxine scaffold for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organic chemistry research to create complex chelating ligands or organocatalysts for asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	4H-1,3-Benzodioxine-7-Carbonyl Chloride, 97%
CAS No.	499770-84-2
Molecular Formula	C10H7ClO3
Molecular Weight	210.61 g/mol
Synonyms	7-(Chlorocarbonyl)-4H-1,3-benzodioxine; 4H-1,3-Benzodioxine-7-carboxylic acid chloride; 1,3-Benzodioxine-7-carbonyl chloride; 7-Carboxy-4H-1,3-benzodioxine chloride; Benzodioxine-7-carbonyl chloride; 499770-84-2; 4H-Benzo[d][1,3]dioxine-7-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4H-1,3-Benzodioxine-7-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.