Description

Glucocerebrosides CAS NO 497155-61-0 are a class of biologically significant glycosphingolipids, serving as the natural substrate for the enzyme glucocerebrosidase. This compound is of paramount importance in biochemical research, particularly for studying lysosomal storage disorders such as Gaucher's disease. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity substrates for enzyme activity assays, inhibitor screening, and the development of therapeutic monitoring tools.

Application

• Enzyme Substrate for Research: Critical substrate for in vitro assays to measure glucocerebrosidase (GBA) enzyme activity.
• Drug Discovery & Development: Used in high-throughput screening (HTS) platforms to identify and characterize potential pharmacological chaperones and enzyme replacement therapy (ERT) candidates.
• Diagnostic Reagent Manufacturing: A key component in the production of diagnostic kits for the detection and monitoring of Gaucher's disease.
• Biochemical Pathway Studies: Employed in research to elucidate the sphingolipid metabolism pathway and its role in cellular function and disease.
• Quality Control Reference Standard: Serves as a certified reference material (CRM) for quality assurance in pharmaceutical production and clinical laboratories.
• Academic & Institutional Research: Fundamental tool for universities and research institutes studying lysosomal biology, inherited metabolic diseases, and lipid biochemistry.

Basic Information

Product Name	Glucocerebrosides
CAS No.	497155-61-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Glucosylceramide; D-Glucosyl-β1-1'-N-acylsphingosine; β-Glucocerebroside; Gaucher's Disease Substrate; GlcCer; D-Glucosylceramide; N-Acyl-D-glucosylsphingosine; Ceramide Glucoside
EINECS	Contact for details

Quality Control

Our Glucocerebrosides are manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for biochemical reagents to support our clients' compliance needs in pharmaceutical development and clinical diagnostics.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in suitable organic solvent mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.